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3PKSTUDIES3CLINICAL STUDIESJOINT, DOMS, OA1META-ANALYSIS ANDSYSTEMATIC REVIEWApplication versatilityWater dispersibility offers versatilityin applications such as powderedbeverages, stick packs, capsules, tablets, gummies & chews, shots& RTDs-3 human pharmacokinetic trials confirming in-studybio-equivalence of 250mg TurmXTRA™ 60N with 1575mgTurmeric Extract (95% curcuminoids)-2 clinical trials in healthy human subjects have proven theefficacy of TurmXTRA™ 60N in improving joint comfort andproviding with muscle relief-1 clinical trial in subjects with osteoarthritis has establishedclinical efficacy of TurmXTRA™ 60N in improving joint mobilityand comfort while reducing inflammatory biomarkersAward winning ingredient Higher consumer complianceA low one-a-day dose provides higher consumer compliance.Application easeTurmXTRA™ 60N's ~ 250mg one-a-day dose provides efficacy and unprecedented flexibility in combining turmeric with complementary ingredients to enhance your formulation.All-naturalNo use of synthetic excipients and surfactants.A complete clinical packageLearn more >World's first Curcuma longaingredient with a completeclinical package at 250mgone-a-day dose.Any of these statements have not been evaluated by the Food and Drug Administration. This ingredient is not intended to diagnose, treat cure, or prevent any disease.TurmXTRA™ mark is a registered trademark of Nutriventia Limited.5

A complete clinical package3 PHARMACOKINETIC STUDYSTUDY 1 AND STUDY 2 – One 250 mg dose of TurmXTRA™60N is clinically substantiated to show equivalenceto three 500 mg doses of standard 95% turmeric extract. Our 2 separate Human PKstudies drew the same set of results which guaranteed consistent quality ofTurmXTRA™60N.Pharmacokinetic study 1Source: Thanawala S, Shah R, Alluri KV, Somepalli V, Vaze S, Upadhyay V. Comparative bioavailability of curcuminoidsfrom a water-dispersible high curcuminoid turmeric extract against a generic turmeric extract: a randomized, cross-over,comparative, pharmacokinetic study. J Pharm Pharmacol. 2021 Apr 27;73(6):816-823. doi: 10.1093/jpp/rgab028.PMID: 33755149.Time (h)Mean plasma concentration of totalcurcuminoids (ng/mL)004 8 121020 24203040506070809016TurmXTRA™60N Std 95%TETurmXTRA™60N Time (h)Mean plasma concentration of totalcurcuminoids (ng/mL)004 8 121020 24203040506016Std 95%TEPharmacokinetic study 2STUDY 3 -One 250 mg dose of TurmXTRA™60N is clinically substantiated to show comparable kinetics to three 500 mg doses of a branded turmeric extract plus piperine taken at three different time intervals. Source: Thanawala S, Shah R, Doyle L, Upadhyay V. Comparative pharmacokinetics of curcuminoids from waterdispersible turmeric extract against a curcuminoids-piperine combination : An open label, randomized, balanced,2-Treatment, 2-Sequence, 2-Period Crossover Study. Alt Ther. 2024 Apr; 30 (4) : 18-23Any of these statements have not been evaluated by the Food and Drug Administration. This ingredient is not intended to diagnose, treat cure, or prevent any disease.TurmXTRA™ mark is a registered trademark of Nutriventia Limited.Pharmacokinetic study 3Mean plasma concentration of totalcurcuminoids (ng/mL)004 6 81020 2420304050607016TurmXTRA™ 60N Branded 95% TE+5mg piperineTime (h)

TurmXTRA™60N PlaceboSource: Thanawala S, Shah R, Karlapudi V, Desomayanandam P, Bhuvanendran A. Efficacy and Safety of TurmXTRA® 60N in Delayed Onset MuscleSoreness in Healthy, Recreationally Active Subjects: A Randomized, Double-Blind, Placebo-Controlled Trial. Evid Based Complement AlternatMed. 2022 Aug 5;2022:9110414. doi: 10.1155/2022/9110414. PMID: 35966736; PMCID: PMC9374544.STUDY 5 - DELAYED ONSET MUSCLE SORENESS DOMS STUDYOur randomized, double-blind, placebo-controlled trial on 30 healthy and recreationally active subjects showed the efficacy of TurmXTRA™60N in reducing muscle soreness and increasing psychological well-being.Change in Recovery Timecompared to placeboChange in Muscle Soreness Recovery as compared to placeboHigher levels of recovery96 hrs post-workout1.5x improvementTime (hr)Percentage RecoveryFaster recoveryIn H&M - Fatigue Scale4x fasterChange in LDH levelscompared to placeboBetter Recovery72 hrs post-workout~9x improvementLDH levelsChange in time in80-meter fast-paced walkMore agility~2x improvementJoint comfortimprovement19%Mobilityimprovement2xOur randomized, double-blind placebo-controlled study on 96 healthy volunteers showed the efficacy of TurmXTRA™60N on joint health with significant results.Time (s)Change in pain (VAS) after80-meter fast-paced walkMore comfort~3x improvementVASChange in time in9-stair climbMore agility~1.5x improvementTime (s)TurmXTRA™60N PlaceboSource: Thanawala S, Shah R, Alluri KV, Somepalli V, Vaze S, Upadhyay V. Comparative bioavailability of curcuminoids from a water-dispersiblehigh curcuminoid turmeric extract against a generic turmeric extract: a randomized, cross-over, comparative, pharmacokinetic study. J PharmPharmacol. 2021 Apr 27;73(6):816-823. doi: 10.1093/jpp/rgab028. PMID: 33755149.Journal of Pharmacy and Pharmacology, Oxford University PressSTUDY 4 - JOINT HEALTH STUDYAny of these statements have not been evaluated by the Food and Drug Administration. This ingredient is not intended to diagnose, treat cure, or prevent any disease.TurmXTRA™ mark is a registered trademark of Nutriventia Limited

2.4x improvementVisual analog scale (100 mm)HEALTH BENEFITSJointhealthSkinhealthBrainhealthImmunehealthLiverhealthnutriventia.com | sales@nutriventia.comLICENSES & CERTIFICATIONSScan to visit websitefor more informationOur randomized, double-blind, placebo controlled, parallel group 90-day study on 139 subjects with mild to moderate knee osteoarthritis proved the efficacy and safety of TurmXTRA™60N in significantly reducing pain and improving comfort & knee function.STUDY 6 - OSTEOARTHRITIS STUDYReduced Pain (KOOS) Better Knee FunctionNearly 4x improvement 2.3x improvementTurmXTRA™60N PlaceboChange in pain (VAS) ascompared to placeboBetter Comfort (VAS)Visual analog scale (100 mm)Knee Injury and Osteoarthritis Outcome scoreChange in pain (KOOS)as compared to placeboChange in knee related quality oflife as compared to placeboKOOS – Pain scoreVAS – Pain scoreEase in knee mobility2025 TurmXTRA™ is a registered trademark of Nutriventia Ltd.Thanawala S, Shah R, Alluri K V, Bhupathiraju K, Prasad N, Agarwal N.Efficacy and Safety of a Novel Low-Dose Water-Dispersible Turmeric Extract in the Management of Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Pain Res 2025 Jan 25 ; 18 : 411 – 427.

USP compliantMultiple randomized, double-blind, placebo controlled clinicaltrials validating one-a-day dose for managing stress.Validated with a full clinical package forprolonged release.TMAlso known as ashwanova™ProlanzaTM is a unique long-acting ingredient of ashwagandha root extract which complies to 10 USP Withanolides. It’s innovative release pattern ensures extended clinical benefits.PHARMACOKINETIC STUDY*Compared to a leading branded Ashwagandha ingredient, ProlanzaTM showed -Superior Relative BioavailabilityProlanzaTM has a bioavailability which is nearly12 times higher as compared to the reference product.Extended AvailabilityWithanolides from ProlanzaTM are available in plasma for upto24 hours A comprehensive clinical package0 2 4 6 8 10 12 14 16 18 20 22 2400.511.522.53ReferenceTime (hrs.)Mean plasma concentration of totalwithanolidies (ng/mL)Learn more >Root-only, USP compliant,1-a-day ashwagandha Eervescent TabletsStress SupportSleepHealthMental WellbeingCognitive SupportTabletsGummiesReady-To-DrinkReady-To-Mix5

**STUDY 2 – A STRESS & COGNITIVE HEALTH STUDYRandomized, double-blind, placebo-controlled, 90 days study on 100 healthy subjects with mild to moderate stress. *STUDY 3 – MULTI ARM - STRESS STUDYRandomized, double-blind, placebo-controlled, 60 days, multi arm study on 126 healthy subjects with mild to moderate stressImprovement in subjects taking ProlanzaTM as comparedto Placebo after 60 days Shefali Thanawala*, Rajat Shah, Kiran Bhupathiraju, Krishnaraju Venkata Alluri, Prabakaran Desomayanandanam, Arun BhuvenendranPosted Date: 19 February 2025doi: 10.20944/preprints202502.1076.v2Keywords: ashwagandha; happiness; sleep; stress; sustained- release; withanolides*Preprint available2025 ProlanzaTM is a registered trademark of Nutriventia Ltd.1Perceived stress levels 2Sleep quality3Overall mental well-being3X8.3X4X2.7X6.7X2.34Xnutriventia.com | sales@nutriventia.com

Mimics 8-hour naturalsleep patternMelatonin will capture 58% ($820M) of thehealth sleep market, driven by 65% ofconsumers seeking supplements for sleepmanagement, a prevalent driver of sales.Source - NBJ Condition Specific Report 2023 ; NBJ Herbs and Botanicals Report 2023MARKET INSIGHTSLearn more >Melotime™ is a patent-pending and proprietary extended-release melatonin ingredient that helps mimic the body’s natural sleep pattern and supports quality sleep. The unique release profileof Melotime™ ensures a release of a significant portion in the first hour followed by continuous release of melatonin upto 6 hours for maintenance. This ensures a quick on-set and maintains good quality of sleep.Timed release, melatonin Any of these statements have not been evaluated by the Food and Drug Administration. This ingredient is not intended to diagnose,treat, cure or prevent any disease.Melotime™ is a trademark of Nutriventia Limited.Melotime™ showed upto 50% release in1st hour, with periodic release in a6-hour interval for uninterrupted sleep8-hour sustained sleepSustained release profile helps to get 8 hours of sleep without side effectsSupports natural sleep patternThe unique release profile provides a quick onset and good quality restorative sleep.PRACTICAL APPLICATIONSCapsulesGummies & chewsStick packs(powder)Chocolates

nutriventia.com | sales@nutriventia.comHEALTH BENEFITSSleepregulationAntioxidantsupportCognitivehealthImmunehealthWeightmanagementSUSTAINED RELEASE PROFILEReleases upto 50% in the first hourSubsequent release per hour in smaller burstsExtended action through sustained release profile of Melotime™Extended half-life (T1/2) –5.1 h for Melotime vs 1.01 h for Melatonin IRPHARMACOKINETIC STUDYMelotime™ Melatonin IRTime (h)0180001600014000120001000080006000400020000Mean plasma concentration ofmelatonin (pg/mL)1 2 3 4 5 6 7 8Disturbed sleepSound sleepFastereliminationSlowereliminationScan to visit websitefor more informationLICENSES & CERTIFICATIONSSource - Thanawala S, Abiraamasundari R, Shah R. Comparative pharmacokinetics of Sustained-release versus Immediate-releasemelatonin capsules in Fasting healthy adults : a randomized, open-label, cross-over study. Pharmacokinetics. 16, 1248.© 2025 Melotime™. All rights reserved.

Caffeine stimulates the nervous system leading to improved alertness, exemplified motor coordination, and recharged focus. The most significant issue with caffeine is that its effects start to diminish after a couple of hours dueto quick absorption of caffeine within the body. High and/or multiple doses leads to caffeine tolerance which could lead to jitteriness, headache, and nervousness collectivelyknown as ‘caffeine crash’. CaffXtend™ is a unique patented product that delivers natural caffeine for 12 hours, from a natural matrix using our proprietary modified-release technology.Long-acting caffeine 79% active consumers consume supplements to improve energy and stamina.63% of these consumers prefer natural sourceof caffeine in their sports nutrition products.Source - NBJMARKET INSIGHTSHEALTH BENEFITSImproved focus andmental alertness APPLICATIONSGummiesStick packs(powder)All-naturalSource of natural caffeine is fromcoffee seeds. This caffeine is embedded in a natural release controlling matrix.One-a-day doseA single dose designed for an enhanced caffeine experience, lasting up to 12 hours, offers all-day alertness and focus.Any of these statements have not been evaluated by the Food and Drug Administration. This ingredient is not intended to diagnose, treat, cure, or prevent any disease.CaffXtend™ mark is a registered trademark of Nutriventia Limited.HardcapsulesEffervescent TabletsStick PacksChocolatesCaffXtend™ provides 400% lesserperception of fatigue in comparison toregular natural caffeineLearn more >12 hour Boost forfocus & alertness

SUSTAINED RELEASE PROFILEClinically substantiated to reduce perception of ‘tiredness’ for an extended duration (12 hours) from a single doseThe sustained release of caffeine gives 12 hours of enhanced energy* and focus*The claims of energy are more in terms of the general meaning of the word rather than energy as referred to as ATP productionExtended action through sustainedrelease profile of CaffXtend™1.Extended Tmax – 391.57%(to reach maximum concentration)Extended half-life T½ – 22.32% longerSignificantly lower scoresfor ‘tired’ and ‘jittery’3.Lesser perception of tiredness and jittersLower scores for parametersindicative of ‘caffeine crash’4.No caffeine crash, hence saferExtended efficacy through sustainedrelease profile of CaffXtend™ from a Caff-VAS (Caffeine Research Visual Analog Scales)** significantly higher scores for ‘overall mood’, ‘relaxed’and ‘alert’2.Better mood & more alertnessCaffXtend™ is beneficial with better efficacy, as compared to repeated caffeine dosing5.Substantiated from data of human clinical trialcompared with equal dose of natural caffeinePHARMACOKINETIC STUDY#Source: Shefali Thanawala, Rajat Shah, R. Abiraamasundari, R. Senthurselvi & PrabakaranDesomayanandam (2023): Comparative Bioavailability and Benefits on Mental Functions ofNovel Extended-Release Caffeine Capsules against Immediate-Release Caffeine Capsules:An Open-Label, Randomized, Cross-over, Single-Dose Two-Way Crossover Study, Journalof Dietary Supplements, DOI: 10.1080/19390211.2022.2160529LICENSES & CERTIFICATIONSnutriventia.com | sales@nutriventia.comScan to visit websitefor more informationSharp declineImmediate spikeProgressiveincreaseGradualdeclineMean concentration (pg/ml)0 2 4 6 8 10 120500100015002000250030003500400045005000Time (hrs.) Caffeine IR 2025 CaXtend™ is a registered trademark of Nutriventia Ltd.

C-Fence™ is a direct compressible granularsystem of Vitamin C which is an ideal solutionfor manufacturers targeting convenient andcontinuous 24-hour antioxidant shield. Poweredusing our modified release technology, smallbursts of Vitamin C are consistently releasedperiodically, providing 24-hour antioxidantsupport. Unlike other sustained release productsthat are time-consuming to develop andmanufacture, C-Fence™ just needs a single-stepoperation to compress granules into tablets.24-hour optimised Vitamin Cdirect compressible granulesLong-acting, once a day doseA single dose provides 24-hour protection making it convenient for end consumers.Natural flowVitamin C is inherently hygroscopicwith poor flow properties. However, C-Fence™ crafted using nature-derivedexcipients and patented proprietary process,offers seamless flow, enhancingmanufacturing convenience.Assured consistencyEach batch of C-Fence™ undergoes pre-quality evaluation by testingtablets from a representative sample.Safety with low doseC-Fence™ averts gastric distension bygradually releasing controlled Vitamin Cbursts.60% of consumers incorporate Vitamin C intotheir daily routine to bolster their immune system.Source - NBJ Supplement Business Report 2023MARKET INSIGHTSPRACTICAL APPLICATIONSTabletsAny of these statements have not been evaluated by the Food and Drug Administration. This ingredient is not intended to diagnose,treat, cure, or prevent any disease.C-Fence™ mark is a registered trademark of Nutriventia Limited.Shields you for 24 hourVitamin C protectionLearn more >C-fence™ has shown 12-hour sustainedrelease Vitamin C in-vitro.

PHARMACOKINETIC STUDYClinically substantiated through a randomized double-blind, parallel arm, placebo-controlled clinical trial to evaluate the pharmacokinetic profile of Vitamin C from an extended action tablet from C-Fence™. Clinical trial shows that the 12-hour release profile correspondingly produces a sustained level of Vitamin C in the active state in plasma providing a 24-hour in-vivo coverage.IN VITRO DISSOLUTIONSingle dose provides a consistent release for maximum timePolymer matrixWorks by diffusion mechanism from the matrixRelease in small burstsHEALTH BENEFITSAntioxidantSkinhealthBrainhealthImmunehealthCardiovascularhealthLICENSES & CERTIFICATIONSExtendedTmaxCmax comparedto baseline 0hrs85xC24 compared to baseline 0hrs20xXsales@nutriventia.comShah R, Thanawala S, Abiraamasundari R. Pharmacokinetics of a Novel Sustained-Release Vitamin C Oral Tablet: A Single Dose, Randomized, Double-Blind, Placebo-Controlled Trial. J Pharmacol Pharmacother. 2022 Jul 21 ; 13 : https://doi.org/10.1177/0976500X2211116 69Scan to visit websitefor more informationTime (hrs.)020040060080010001200Avg. concentration of Vit. C (ng/ml)0 2 4 6 8 10 12 14 16 18 20 22 24Placebo85x20x© 2025 C-Fence™. All rights reserved.

In today’s nutraceutical and functional food industries, consumer compliance and product success hinge not just on efficacy, but also on sensory experience-especially taste. Many clinically validated actives, while effective, suffer from bitter, metallic, or otherwise unpleasant flavors that can deter repeat use and reduce compliance. Taste masking is therefore essential: it enhances palatability, increases product acceptance, and ultimately drives better health outcomes and brand loyalty.With a 40+ years of legacy in healthcare and innovating delivery technology platforms, Nutriventia offers a comprehensive suite of taste-masked nutraceutical solutions, ensuring even the most challenging actives become enjoyable for consumers. How it Works:1. FORMULATION-LEVEL MASKING• Applies polymer film-coating, microencapsulation, or lipid barrier systems to the active.• Physically prevents contact between the active and taste receptors on the tongue.• Especially effective for highly bitter or metallic-tasting actives and for use in formats like orally disintegrating tablets and gummies.How it Works:2. PHYSICAL BARRIER ENCAPSULATIONTransforming Nutraceuticals into Palatable,Consumer-Preferred ProductsNutriventia E.D.G.E.™ Taste Masking Technology & SolutionsHOW NUTRIVENTIA MASKS TASTE: THREE INNOVATIVE APPROACHESTHE NEED FOR TASTE MASKING IN NUTRACEUTICALSUses a blend of sweeteners and flavors to overwhelm unpleasant tastes.Targets different taste receptors, activating more “sweetness-perceived” signals in the brain.Ideal for masking mild to moderately bitter actives.Bitter Active CompoundApply Polymer CoatingMicroencapsulationLipid Barrier SystemTaste Masked Active• Uses charged polymers, complexing agents, or ion-exchange resins to bind with actives at the molecular level.• Suppresses bitterness by forming stable complexes that reduce solubility or block taste receptor interaction.• Particularly useful for actives with strong, persistent bitterness or metallic notes.How it Works:3. MOLECULAR COMPLEXATIONReduced Solubility Identify Bitter ActiveSelect Complexing AgentMolecular BindingComplex FormationBitterness SuppressionBlocked Taste Receptor Interaction Molecular Complexation Process

Iron, Made PleasantIron Deficiency/Anemia Maternal HealthPediatric NutritionGeneral WellnessFerrous Fumarate toprevent iron deficiencyLeading iron supplement for iron deficiency and anemia, but strong metallic taste reduces compliance, especially in chewables, powders, and syrups.WHY TASTE MASK FERROUS FUMARATE?• Proprietary encapsulation technology physically isolates ferrous fumarate, preventing its metallic flavor from reaching taste buds.• Maintains iron’s bioavailability and efficacy while making supplementation palatable.• Especially beneficial for pediatric, maternal, and general wellness products.NUTRIVENTIA’S SOLUTIONGinko Biloba:Palatable Brain Health Ferrous Fumarate: Our Taste-Masking ActivesCognitive SupportMemory EnhancementAntioxidant ProtectionCirculatory HealthGinkgo biloba forCognitive health supportGinkgo offers cognitive, antioxidant, and circulatory benefits, but its naturally bitter and astringent taste limits use in consumer-friendly formats.WHY TASTE MASK GINKGO?• Advanced, solvent-free encapsulation and molecular complexation neutralize bitterness and astringency without artificial additives.• Prevents Ginkgo actives from contacting taste receptors, delivering a neutral, palatable ingredient.• Preserves efficacy and bioactivity for all-day mental support.NUTRIVENTIA’S SOLUTIONFeCapletsTabletsGummiesStick PacksLozengesChocolatesSoftgelsPRACTICAL APPLICATIONS FOR GINKO BILOBA & FERROUS FUMARATEnutriventia.com | sales@nutriventia.com© 2025 Nutriventia. All rights reserved.Learn more >Learn more >

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